Consanguinity and Genomics

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منابع مشابه

Consanguinity and chromosomal abnormality

BACKGROUND: Consanguinity is defined as the marriage between close relatives. The deleterious effects associated with consanguinity may be caused by the expression of rare recessive genes inherited from common ancestors. AIMS AND OBJECTIVES: The present study was undertaken to analyze the effect of consanguinity on chromosomal abnormality (CA). METHODS AND MATERIALS: During last 6 years period,...

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Consanguinity and child health

Marriage between close biological kin is widely regarded as genetically disadvantageous in contemporary western societies, but consanguineous unions remain preferential in north africa, the Middle east and large parts of asia, with marriage between first cousins particularly popular. Many major populations also are subdivided into endogamous communities that have distinctive breeding pools. it ...

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Consanguinity and primary immunodeficiencies.

Primary immunodeficiencies (PIDs) are a heterogeneous group of genetic disorders caused by defects in the immune system that predispose patients to infections, autoimmune diseases, lymphoproliferation and malignancies. Most PIDs are inherited in an autosomal recessive pattern; therefore, they are more common in areas with high rates of consanguineous marriage. Reports about PIDs from these area...

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Consanguinity and dysmorphology in Arabs.

Incidence rates of congenital disorders among the 350 million inhabitants of Arab countries could be influenced via the people's demographic and cultural characteristics. Arabs usually marry at a young age and have large families. They share certain core cultural values and beliefs, with the family accepted as the central structure of society. Consanguineous marriage is favored and respected in...

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Consanguinity and apnea of prematurity.

Consanguinity, marriage between relatives, has been associated with perinatal mortality and morbidity. Apnea of prematurity is defined as the cessation of breathing for longer than 20 seconds or that of any duration if accompanied by cyanosis and sinus bradycardia, for infants born before 37 weeks of gestation. The objective of the study was to examine the association between consanguinity and ...

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ژورنال

عنوان ژورنال: Human Heredity

سال: 2014

ISSN: 1423-0062,0001-5652

DOI: 10.1159/000363353